The Endothelial Cell Biology in Health and chronic Disease Research Group
The Endothelial Cell Biology in Health and Chronic Disease research group is dedicated to understanding the contribution of endothelial cells to health, wellbeing and pathophysiology of chronic diseases. Our basic and clinical laboratory research includes diverse range of multidisciplinary projects focused on (1) the characterisation of molecular mechanisms which regulate endothelial cell properties and function in cancer, cardiovascular disease, lymphoedema and chronic lung disease, and (2) the development of fully humanised, and thus clinically relevant, in vitro models using these cells.
Dr Nikitenko (far right) and his current team.
We use a multidisciplinary approach and a range of methods, including 2D and 3D cell culture techniques, proteomics, imaging/microscopy and others, to study the properties and function of endothelial cell.